If your league allows bully ball, it is very hard to stop unless you have comparable bases. If not, then a little creativity goes a long way. Like the previous post, use loopers to cause havoc in the backfield.
You can negate their strongest player by simply not lining up in front of him. Use angles and send blitzes from places your opponent won't expect. Learn to control the game by conning your opponent into doing what you want. He will think he's beating you, but really he'll be playing into your hands.
