Tweaking is used to manipulate the base to do various things. For example bases can be tweaked for strength to use with OL and DL, speed for WR's, RB's, and DB's, and loopers for blitzing OLB's or RB's on sweeps. I can't say that tweaking is the key to success but it plays an important when coaching your team. I will send you a PM that might help wih your tweaking questions.
Coach J
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